- API
Any substance that is represented for use in a drug and that, when used in the manufacturing, processing, or packaging ...
- Active Ingredient
Any component that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, ...
- CAS No.
Unique number assigned to a specific chemical (identified by its chemical name) by the American Chemical Society and ...
10-Hydroxycamptothecin
Catalog No. | PI0002 |
---|---|
CAS No. | 19685-09-7 |
Molecular Formula | C20H16N2O5 |
Molecular Weight | 364.35 |
Purity | 98% HPLC |
Package | 25 kg/drum |
Botanical Source | Camptotheca acuminata |
Appearance | Pale yellow powder |
Storage | Stored in cool and dry places, protected from direct sunlight and heat. |
Shelf Life | 2 years |
Note: This 10-hydroxycamptothecin can also be used as reference standards. You can find it under the category of Reference Substance at Herbalext.com. |
Safety Tips of 10-Hydroxycamptothecin
Handling of 10-hydroxycamptothecin should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.
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Related Researches
- 1. PEG-chitosan-coated iron oxide nanoparticles with high saturated magnetization as carriers of 10-hydroxycamptothecin: preparation, characterization and cytotoxicity studies.
Qu JB, et al. Colloids Surf B Biointerfaces 2013 Feb 1;102:37-44.
- 2. Synthesis, characterization, and antitumor evaluation of the albumin-SN38 conjugate.
Yao Y, et al. Anticancer Drugs 2013 Mar;24(3):270-7.
- 3. Effect of genistein, a natural soy isoflavone, on the pharmacokinetics and intestinal toxicity of irinotecan hydrochloride in rats.
Yokooji T, et al. J Pharm Pharmacol 2013 Feb;65(2):280-91.
- 4. Bioluminescence imaging of DNA synthetic phase of cell cycle in living animals.
Chen ZH, et al. PLoS One 2013;8(1):e53291.
- 5. Assessing the regioselectivity of OleD-catalyzed glycosylation with a diverse set of acceptors.
Zhou M, et al. J Nat Prod 2013 Feb 22;76(2):279-86.
- 6. The relative protein abundance of UGT1A alternative splice variants as a key determinant of glucuronidation activity in vitro.
Rouleau M, et al. Drug Metab Dispos 2013 Apr;41(4):694-7.
- 7. Activation of a PGC-1-related coactivator (PRC)-dependent inflammatory stress program linked to apoptosis and premature senescence.
Gleyzer N, et al. J Biol Chem 2013 Mar 22;288(12):8004-15.
- 8. Enhanced tumor targeting and antitumor efficacy via hydroxycamptothecin-encapsulated folate-modified N-succinyl-N'-octyl chitosan micelles.
Zhu H, et al. J Pharm Sci 2013 Apr;102(4):1318-32.
- 9. Co-delivery of 10-Hydroxycamptothecin with Doxorubicin Conjugated Prodrugs for Enhanced Anticancer Efficacy.
Zhang Y, et al. Macromol Biosci 2013 Feb 18.
- 10. Comparison of the effects of mitomycin C and 10-hydroxycamptothecin on an experimental intraarticular adhesion model in rabbits.
Li X, et al. Eur J Pharmacol 2013 Mar 5;703(1-3):42-5.