- API
Any substance that is represented for use in a drug and that, when used in the manufacturing, processing, or packaging ...
- Active Ingredient
Any component that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, ...
- CAS No.
Unique number assigned to a specific chemical (identified by its chemical name) by the American Chemical Society and ...
Andrographolide
Catalog No. | PI0011 |
---|---|
CAS No. | 5508-58-7 |
Molecular Formula | C20H30O5 |
Molecular Weight | 350.44 |
Purity | 98% HPLC |
Package | 25 kg/drum |
Botanical Source | Andrographis Paniculata (Burm.f) Ness |
Appearance | White powder |
Storage | Stored in cool and dry places, protected from direct sunlight and heat. |
Shelf Life | 2 years |
Note: This andrographolide can also be used as reference standards. You can find it under the category of Reference Substance at Herbalext.com. |
Safety Tips of Andrographolide
Handling of andrographolide should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.
Related Products
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Catalog No.: HE0013
Specification: 40% Polyphenols & 5%-8% Total acids UV
Package: 25 kg/drum
Botanical Source: Apple Cider Vinegar
Related Applications
Respiratory Systems
The respiratory system is a biological system that introduces respiratory gases to the interior and performs gas exchange. Molecules of oxygen and carbon dioxide are passively exchanged, by diffusion, between the gaseous external environment and the blood. Respiratory diseases contain coughing, asthma, pneumonia, etc. Many herbal extract are effective preventatives or cures of these diseases, such as Quercetin and Polydatin etc.Antibacterial and Anti-inflammatory
Antibiotics are medicines that kill microorganisms and cure bacterial infections. Conventional medicine has produced a number of antibiotics, which doctors prescribe for a variety of infectious conditions. There are also several herbs used as natural antibiotics that are considered antibacterial or antimicrobial. Some medicines not only have an anesthetization function but also have the ability to decrease swelling, alleviate pain, resist bacteria, diminish inflammation, disinfect and sterilize. Herbal extract possesses these activities with lower toxicities.
Related Researches
- 1. Mechanisms of Andrographolide-Induced Platelet Apoptosis in Human Platelets: Regulatory Roles of the Extrinsic Apoptotic Pathway.
Lien LM, et al. Phytother Res 2013 Jan 4.
- 2. The HLJ1-targeting drug screening identified Chinese herb andrographolide that can suppress tumour growth and invasion in non-small-cell lung cancer.
Lai YH, et al. Carcinogenesis 2013 May;34(5):1069-80.
- 3. Engineered andrographolide nanoparticles mitigate paracetamol hepatotoxicity in mice.
Roy P, et al. Pharm Res 2013 May;30(5):1252-62.
- 4. Changes in the contents of four active diterpenoids at different growth stages in Andrographis paniculata (Burm.f.) Nees (Chuanxinlian).
Pholphana N, et al. Chin Med 2013 Jan 15;8(1):2.
- 5. Chemical constituents of Caesalpinia decapetala (Roth) Alston.
Wei XH, et al. Molecules 2013 Jan 22;18(1):1325-36.
- 6. Simultaneous determination of 9-dehydro-17-hydro-andrographolide and sodium 9-dehydro-17-hydro-andrographolide-19-yl sulfate in rat plasma by UHPLC-ESI-MS/MS after administration of xiyanping injection: application to a pharmacokinetic study.
Chong L, et al. Biomed Chromatogr 2013 Jan 25.
- 7. Taxifolin enhances andrographolide-induced mitotic arrest and apoptosis in human prostate cancer cells via spindle assembly checkpoint activation.
Zhang ZR, et al. PLoS One 2013;8(1):e54577.
- 8. Improving the efficacy of conventional therapy by adding andrographolide sulfonate in the treatment of severe hand, foot, and mouth disease: a randomized controlled trial.
Li X, et al. Evid Based Complement Alternat Med 2013;2013:316250.
- 9. Andrographolide protects against LPS-induced acute lung injury by inactivation of NF-κB.
Zhu T, et al. PLoS One 2013;8(2):e56407.
- 10. Biological activities and corresponding SARs of andrographolide and its derivatives.
Zhou B, et al. Mini Rev Med Chem 2013 Feb;13(2):298-309.