- API
Any substance that is represented for use in a drug and that, when used in the manufacturing, processing, or packaging ...
- Active Ingredient
Any component that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, ...
- CAS No.
Unique number assigned to a specific chemical (identified by its chemical name) by the American Chemical Society and ...
Escin
Catalog No. | PI0126 |
---|---|
CAS No. | 6805-41-0 |
Molecular Formula | C55H86O24 |
Molecular Weight | 1131.26 |
Purity | 20%-90% HPLC |
Package | 25 kg/drum |
Botanical Source | Aesculus hippocastanum (the horse chestnut) |
Appearance | White powder |
Shelf Life | 2 years |
Note: This escin can also be used as reference standards. You can find it under the category of Reference Substance at Herbalext.com. |
Safety Tips of Escin
Handling of escin should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.
Related Applications
Antibacterial and Anti-inflammatory
Antibiotics are medicines that kill microorganisms and cure bacterial infections. Conventional medicine has produced a number of antibiotics, which doctors prescribe for a variety of infectious conditions. There are also several herbs used as natural antibiotics that are considered antibacterial or antimicrobial. Some medicines not only have an anesthetization function but also have the ability to decrease swelling, alleviate pain, resist bacteria, diminish inflammation, disinfect and sterilize. Herbal extract possesses these activities with lower toxicities.Blood Pressure Regulation
High blood pressure, also known as hypertension, is the most common cardiovascular disease. Blood pressure refers to the force of blood pushing against artery walls as it courses through the body. This puts people at risk of heart disease, stroke and even kidney disease. One in three adults has high blood pressure, especially among the elderly. However, about 21% of sufferers do not even know they have it. Plant extracts provide a more secure and reliable means of regulating blood pressure.
Related Researches
- 1. Sodium beta-aescin may be an effective therapeutic agent for Bell's palsy.
Liu J, et al. Med Hypotheses 2008 Nov;71(5):762-4.
- 2. Use of escin as a perforating agent on the IonWorks quattro automated electrophysiology platform.
Morton MJ, et al. J Biomol Screen 2013 Jan;18(1):128-34.
- 3. Interaction between titanium and cadmium in various guinea pig organs.
Takano T, et al. Biol Trace Elem Res 2013 Feb;151(2):209-16.
- 4. Escin inhibits type I allergic dermatitis in a novel porcine model.
Sipos W, et al. Int Arch Allergy Immunol 2013;161(1):44-52.
- 5. A novel GABAergic action mediated by functional coupling between GABAB-like receptor and two different high-conductance K+ channels in cricket Kenyon cells.
Nakamura A, et al. J Neurophysiol 2013 Apr;109(7):1735-45.
- 6. A Rapid Method for Total Β-Escin Analysis in Dry, Hydroalcoholic and Hydroglycolic Extracts of Aesculus hippocastanum L. by Capillary Zone Electrophoresis.
Dutra LS, et al. Phytochem Anal 2013 Mar 19.
- 7. Synergistic protective effects of escin and low?dose glucocorticoids on blood?retinal barrier breakdown in a rat model of retinal ischemia.
Zhang F, et al. Mol Med Rep 2013 May;7(5):1511-5.
- 8. Preparation, purification and regioselective functionalization of protoescigenin-the main aglycone of escin complex.
Gruza MM, et al. Molecules 2013 Apr 15;18(4):4389-402.
- 9. 3',4'-Dihydroxyflavonol reduces vascular contraction through Ca²? desensitization in permeabilized rat mesenteric artery.
Kim HY, et al. Naunyn Schmiedebergs Arch Pharmacol 2012 Feb;385(2):191-202.
- 10. The antinociceptive effect of intrathecal escin in the rat formalin test.
Li Q, et al. Eur J Pharmacol 2012 Jan 15;674(2-3):234-8.
- 11. Comparative pharmacokinetics and bioavailability of escin Ia and isoescin Ia after administration of escin and of pure escin Ia and isoescin Ia in rat.
Wu XJ, et al. J Ethnopharmacol 2012 Jan 6;139(1):201-6.