- API
Any substance that is represented for use in a drug and that, when used in the manufacturing, processing, or packaging ...
- Active Ingredient
Any component that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, ...
- CAS No.
Unique number assigned to a specific chemical (identified by its chemical name) by the American Chemical Society and ...
Nobiletin
Catalog No. | PI0095 |
---|---|
CAS No. | 478-01-3 |
Molecular Formula | C21H22O8 |
Molecular Weight | 402.39 |
Purity | 98% HPLC |
Package | 25 kg/drum |
Botanical Source | Citrus nobilis Lour |
Appearance | White powder |
Storage | Stored in cool and dry places, protected from direct sunlight and heat. |
Shelf Life | 2 years |
Note: This nobiletin can also be used as reference standards. You can find it under the category of Reference Substance at Herbalext.com. |
Safety Tips of Nobiletin
Handling of nobiletin should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.
Related Applications
Antibacterial and Anti-inflammatory
Antibiotics are medicines that kill microorganisms and cure bacterial infections. Conventional medicine has produced a number of antibiotics, which doctors prescribe for a variety of infectious conditions. There are also several herbs used as natural antibiotics that are considered antibacterial or antimicrobial. Some medicines not only have an anesthetization function but also have the ability to decrease swelling, alleviate pain, resist bacteria, diminish inflammation, disinfect and sterilize. Herbal extract possesses these activities with lower toxicities.
Related Researches
- 1. Chemical constituents of Arisaema franchetianum tubers.
Su Y, et al. J Asian Nat Prod Res 2013;15(1):71-7.
- 2. Antioxidant activity and effective compounds of immature calamondin peel.
Yu MW, et al. Food Chem 2013 Feb 15;136(3-4):1130-5.
- 3. Polymethoxyflavones as agents that prevent formation of cataract: nobiletin congeners show potent growth inhibitory effects in human lens epithelial cells.
Miyata Y, et al. Bioorg Med Chem Lett 2013 Jan 1;23(1):183-7.
- 4. Citrus flavonoids and lipid metabolism.
Assini JM, et al. Curr Opin Lipidol 2013 Feb;24(1):34-40.
- 5. Identification of active compounds from Aurantii Immatri Pericarpium attenuating brain injury in a rat model of ischemia-reperfusion.
Yang EJ, et al. Food Chem 2013 May 1;138(1):663-70.
- 6. Nobiletin-rich Citrus reticulata peels, a kampo medicine for Alzheimer's disease: a case series.
Seki T, et al. Geriatr Gerontol Int 2013 Jan;13(1):236-8.
- 7. Phytochemical profile and antioxidant activity of physiological drop of citrus fruits.
Sun Y, et al. J Food Sci 2013 Jan;78(1):C37-42.
- 8. Characteristics of nobiletin-mediated alteration of gene expression in cultured cell lines.
Nemoto K, et al. Biochem Biophys Res Commun 2013 Feb 15;431(3):530-4.
- 9. Nobiletin Induces Apoptosis and Potentiates the Effects of the Anticancer Drug 5-Fluorouracil in p53-Mutated SNU-16 Human Gastric Cancer Cells.
Moon JY, et al. Nutr Cancer 2013 Feb;65(2):286-95.
- 10. Nobiletin attenuates metastasis via both ERK and PI3K/Akt pathways in HGF-treated liver cancer HepG2 cells.
Shi MD, et al. Phytomedicine 2013 Mar 25.