- API
Any substance that is represented for use in a drug and that, when used in the manufacturing, processing, or packaging ...
- Active Ingredient
Any component that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, ...
- CAS No.
Unique number assigned to a specific chemical (identified by its chemical name) by the American Chemical Society and ...
Sanguinarine
Catalog No. | PI0120 |
---|---|
CAS No. | 2447-54-3 |
Molecular Formula | C20H14N04 |
Molecular Weight | 332.33 |
Purity | 98% HPLC |
Package | 25 kg/drum |
Botanical Source | Macleaya cordata (Willd.) R. Br. |
Appearance | Yellow powder |
Storage | Stored in cool and dry places, protected from direct sunlight and heat. |
Shelf Life | 2 years |
Note: This sanguinarine can also be used as reference standards. You can find it under the category of Reference Substance at Herbalext.com. |
Safety Tips of Sanguinarine
Handling of sanguinarine should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.
Related Products
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Catalog No.: HE0148
Specification: 10%-90% Alpha-Mangostin 3%-8% Gamma-Mangostin HPLC; 30% Polyphenols UV
Package: 25 kg/drum
Botanical Source: Mangosteen
Related Applications
Liver Protection
The liver is the primary organ responsible for expelling and breaking down toxins entering the body. In particular, it produces bile, a detoxifying agent metabolically indispensable in breaking down fats from food. Many chemicals from nature could protect liver to help the process of detoxication.Antibacterial and Anti-inflammatory
Antibiotics are medicines that kill microorganisms and cure bacterial infections. Conventional medicine has produced a number of antibiotics, which doctors prescribe for a variety of infectious conditions. There are also several herbs used as natural antibiotics that are considered antibacterial or antimicrobial. Some medicines not only have an anesthetization function but also have the ability to decrease swelling, alleviate pain, resist bacteria, diminish inflammation, disinfect and sterilize. Herbal extract possesses these activities with lower toxicities.Antineoplastic
Each year, more and more people are getting cancer, especially lung and liver cancer. However, there are not enough good anti-cancer drugs. Fortunately, many herbal extracts have good antineoplastic activity. A plant-based diet can help shield you from cancer because plants are rich in anti-inflammatory and antioxidant substances that help us withstand exposure to ultraviolet radiation, air pollution and other noxious substances.
Related Researches
- 1. A sensitive and selective liquid chromatography-tandem mass spectrometry method for simultaneous determination of five isoquinoline alkaloids from Chelidonium majus L. in rat plasma and its application to a pharmacokinetic study.
Zhou Q, et al. J Mass Spectrom 2013 Jan;48(1):111-8.
- 2. Isolation and characterization of a cDNA encoding (S)-cis-N-methylstylopine 14-hydroxylase from opium poppy, a key enzyme in sanguinarine biosynthesis.
Beaudoin GA, et al. Biochem Biophys Res Commun 2013 Feb 15;431(3):597-603.
- 3. Elucidating the regulon of multidrug resistance regulator RarA in Klebsiella pneumoniae.
De Majumdar S, et al. Antimicrob Agents Chemother 2013 Apr;57(4):1603-9.
- 4. Integration of transcriptome, proteome and metabolism data reveals the alkaloids biosynthesis in Macleaya cordata and Macleaya microcarpa.
Zeng J, et al. PLoS One 2013;8(1):e53409.
- 5. Protective effect of sanguinarine against acetic acid-induced ulcerative colitis in mice.
Niu X, et al. Toxicol Appl Pharmacol 2013 Mar 15;267(3):256-65.
- 6. Sanguinarine and its potent antineoplastic effects in systemic malignancies.
Kapoor S. Nucleic Acid Ther 2013 Apr;23(2):166.
- 7. Capillary electrophoretic study of the synergistic biological effects of alkaloids from Chelidonium majus L. in normal and cancer cells.
Kulp M, et al. Anal Bioanal Chem 2013 Apr;405(10):3391-7.
- 8. Benzylisoquinoline Alkaloid Metabolism: A Century of Discovery and a Brave New World.
Hagel JM, et al. Plant Cell Physiol 2013 Mar 17.
- 9. Opposition between PKC isoforms regulates histone deimination and neutrophil extracellular chromatin release.
Neeli I, et al. Front Immunol 2013;4:38.
- 10. Identification of drug candidate for osteoporosis by computational bioinformatics analysis of gene expression profile.
Yu G, et al. Eur J Med Res 2013 Mar 1;18:5.