- API
Any substance that is represented for use in a drug and that, when used in the manufacturing, processing, or packaging ...
- Active Ingredient
Any component that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, ...
- CAS No.
Unique number assigned to a specific chemical (identified by its chemical name) by the American Chemical Society and ...
Tanshinone I
Catalog No. | PI0137 |
---|---|
CAS No. | 568-73-0 |
Molecular Formula | C19H18O3 |
Molecular Weight | 294.34 |
Purity | 98% HPLC |
Package | 25 kg/drum |
Appearance | Powder |
Shelf Life | 2 years |
Note: This tanshinone i can also be used as reference standards. You can find it under the category of Reference Substance at Herbalext.com. |
Safety Tips of Tanshinone I
Handling of tanshinone i should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.
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Botanical Source: Semen Litchi
Related Applications
Weight Loss
Anti-obesity medication or weight loss drugs are pharmacological agents that reduce or control weight. Obesity is recognized as a social problem, associated with serious health risks and increased mortality. Numerous trials have been conducted to find and develop new anti-obesity drugs through herbal sources to minimize adverse reactions associated with the present anti-obesity drugs.
Related Researches
- 1. Tanshinone derivatives: a patent review (January 2006 - September 2012).
Tian XH, et al. Expert Opin Ther Pat 2013 Jan;23(1):19-29.
- 2. Enzyme kinetic and molecular docking studies for the inhibitions of miltirone on major human cytochrome P450 isozymes.
Zhou X, et al. Phytomedicine 2013 Feb 15;20(3-4):367-74.
- 3. Tanshinone I Activates the Nrf2-Dependent Antioxidant Response and Protects Against As(III)-Induced Lung Inflammation In Vitro and In Vivo.
Tao S, et al. Antioxid Redox Signal 2013 Mar 21.
- 4. Tanshinones Inhibit Amyloid Aggregation by Amyloid-β Peptide, Disaggregate Amyloid Fibrils, and Protect Cultured Cells.
Wang Q, et al. ACS Chem Neurosci 2013 Mar 29.
- 5. Conical coils counter-current chromatography for preparative isolation and purification of tanshinones from Salvia miltiorrhiza Bunge.
Liang J, et al. J Chromatogr A 2013 May 3;1288:35-9.
- 6. PF2401-SF, standardized fraction of Salvia miltiorrhiza shows anti-inflammatory activity in macrophages and acute arthritis in vivo.
Jiang WY, et al. Int Immunopharmacol 2013 Apr 10.
- 7. Bioassay-guided isolation of fatty acid synthase inhibitory diterpenoids from the roots of Salvia miltiorrhiza Bunge.
Jang TS, et al. Arch Pharm Res 2012 Mar;35(3):481-6.
- 8. Tanshinones inhibit the growth of breast cancer cells through epigenetic modification of Aurora A expression and function.
Gong Y, et al. PLoS One 2012;7(4):e33656.
- 9. Growth-inhibitory and apoptosis-inducing effects of tanshinones on hematological malignancy cells and their structure-activity relationship.
Li H, et al. Anticancer Drugs 2012 Sep;23(8):846-55.
- 10. Molecular docking and enzyme kinetic studies of dihydrotanshinone on metabolism of a model CYP2D6 probe substrate in human liver microsomes.
Zhou X, et al. Phytomedicine 2012 May 15;19(7):648-57.