- API
Any substance that is represented for use in a drug and that, when used in the manufacturing, processing, or packaging ...
- Active Ingredient
Any component that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, ...
- CAS No.
Unique number assigned to a specific chemical (identified by its chemical name) by the American Chemical Society and ...
Diosmin
Catalog No. | PI0051 |
---|---|
CAS No. | 520-27-4 |
Molecular Formula | C28H32O15 |
Molecular Weight | 608.54 |
Purity | 90% HPLC |
Package | 25 kg/drum MOQ:200 kg |
Botanical Source | Citrus Aurantium L. or Bitter Orange |
Appearance | Light yellow powder |
Shelf Life | 2 years |
Safety Tips of Diosmin
Handling of diosmin should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.
Related Applications
Blood Pressure Regulation
High blood pressure, also known as hypertension, is the most common cardiovascular disease. Blood pressure refers to the force of blood pushing against artery walls as it courses through the body. This puts people at risk of heart disease, stroke and even kidney disease. One in three adults has high blood pressure, especially among the elderly. However, about 21% of sufferers do not even know they have it. Plant extracts provide a more secure and reliable means of regulating blood pressure.
Related Researches
- 1. Enhancement of the water solubility of flavone glycosides by disruption of molecular planarity of the aglycone moiety.
Lewin G, et al. J Nat Prod 2013 Jan 25;76(1):8-12.
- 2. Simultaneous quantification and validation of caffeoylquinic acids and flavonoids in Hemistepta lyrata and peroxynitrite-scavenging activity.
Nugroho A, et al. J Pharm Biomed Anal 2013 Mar 25;76:139-44.
- 3. Diosmin protects against trichloroethylene-induced renal injury in Wistar rats: plausible role of p53, Bax and caspases.
Rehman MU, et al. Br J Nutr 2013 Feb 12:1-12.
- 4. The effect of diosmin on pancreatic injury induced by hepatic ischemia reperfusion in rats.
Kilicoglu SS, et al. Bratisl Lek Listy 2013;114(3):119-24.
- 5. Diosmin protects against ethanol-induced hepatic injury via alleviation of inflammation and regulation of TNF-α and NF-κB activation.
Tahir M, et al. Alcohol 2013 Mar;47(2):131-9.
- 6. [Bioflavonoids and their significance in angiology: focus on diosmin.]
Bogachev VI, et al. Angiol Sosud Khir 2013;19(1):73-81. Russian.
- 7. Synergistic effects of diosmetin with erythromycin against ABC transporter over-expressed methicillin-resistant Staphylococcus aureus (MRSA) RN4220/pUL5054 and inhibition of MRSA pyruvate kinase.
Chan BC, et al. Phytomedicine 2013 May 15;20(7):611-4.
- 8. Modeling Anti-Allergic Natural Compounds by Molecular Topology.
García-Domenech R, et al. Comb Chem High Throughput Screen 2013 Apr 16.
- 9. Diosmin reduces calcium oxalate deposition and tissue degeneration in nephrolithiasis in rats: a stereological study.
Noorafshan A, et al. Korean J Urol 2013 Apr;54(4):252-7.
- 10. Diosmin Alleviates Retinal Edema by Protecting the Blood-Retinal Barrier and Reducing Retinal Vascular Permeability during Ischemia/Reperfusion Injury.
Tong N, et al. PLoS One 2013 Apr 24;8(4):e61794.