- API
Any substance that is represented for use in a drug and that, when used in the manufacturing, processing, or packaging ...
- Active Ingredient
Any component that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, ...
- CAS No.
Unique number assigned to a specific chemical (identified by its chemical name) by the American Chemical Society and ...
Honokiol
Catalog No. | PI0073 |
---|---|
CAS No. | 35354-74-6 |
Molecular Formula | C18H18O2 |
Molecular Weight | 266.33 |
Purity | 98% HPLC |
Package | 25 kg/drum |
Botanical Source | Magnolia officinalis Rehd.et Wils. |
Appearance | White powder |
Storage | Stored in cool and dry places, protected from direct sunlight and heat. |
Shelf Life | 2 years |
Note: This honokiol can also be used as reference standards. You can find it under the category of Reference Substance at Herbalext.com. |
Safety Tips of Honokiol
Handling of honokiol should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.
Related Products
-
Catalog No.: HE0149
Specification: 5%-98% Lutein (Xanthophyll) HPLC 5%, 20%, 50% Zeaxanthin HPLC
Package: 25 kg/drum
Botanical Source: Marigold
Related Applications
Antibacterial and Anti-inflammatory
Antibiotics are medicines that kill microorganisms and cure bacterial infections. Conventional medicine has produced a number of antibiotics, which doctors prescribe for a variety of infectious conditions. There are also several herbs used as natural antibiotics that are considered antibacterial or antimicrobial. Some medicines not only have an anesthetization function but also have the ability to decrease swelling, alleviate pain, resist bacteria, diminish inflammation, disinfect and sterilize. Herbal extract possesses these activities with lower toxicities.Antineoplastic
Each year, more and more people are getting cancer, especially lung and liver cancer. However, there are not enough good anti-cancer drugs. Fortunately, many herbal extracts have good antineoplastic activity. A plant-based diet can help shield you from cancer because plants are rich in anti-inflammatory and antioxidant substances that help us withstand exposure to ultraviolet radiation, air pollution and other noxious substances.Antioxidant Supplements
Antioxidants are one kind of molecules, helping to neutralize harmful free radicals which can accelerate cellular oxidation. They provide an important and solid defense against the diseases caused by oxidative stress, such as cancer, heart disease, decline in brain function, immune system and aging. Because antioxidants are capable of stabilizing or deactivating the free radicals from oxidation reactions before they attack cells.
Related Researches
- 1. Honokiol synergizes chemotherapy drugs in multidrug resistant breast cancer cells via enhanced apoptosis and additional programmed necrotic death.
Tian W, et al. Int J Oncol 2013 Feb;42(2):721-32.
- 2. Honokiol protects rat hearts against myocardial ischemia reperfusion injury by reducing oxidative stress and inflammation.
Wang Y, et al. Exp Ther Med 2013 Jan;5(1):315-319.
- 3. Honokiol inhibits the inflammatory reaction during cerebral ischemia reperfusion by suppressing NF-κB activation and cytokine production of glial cells.
Zhang P, et al. Neurosci Lett 2013 Feb 8;534:123-7.
- 4. Honokiol induces caspase-independent paraptosis via reactive oxygen species production that is accompanied by apoptosis in leukemia cells.
Wang Y, et al. Biochem Biophys Res Commun 2013 Jan 18;430(3):876-82.
- 5. Magnolia polyphenols attenuate oxidative and inflammatory responses in neurons and microglial cells.
Chuang DY, et al. J Neuroinflammation 2013 Jan 29;10:15.
- 6. Maximizing dermal targeting and minimizing transdermal penetration by magnolol/honokiol methoxylation.
Lin CF, et al. Int J Pharm 2013 Mar 10;445(1-2):153-62.
- 7. Screening active anti-breast cancer compounds from Cortex Magnolia officinalis by 2D LC-MS.
Hou X, et al. J Sep Sci 2013 Feb;36(4):706-12.
- 8. Predicting in silico which mixtures of the natural products of plants might most effectively kill human leukemia cells?
El-Shemy HA, et al. Evid Based Complement Alternat Med 2013;2013:801501.
- 9. Honokiol blocks store operated calcium entry in CHO cells expressing the M3 muscarinic receptor: honokiol and muscarinic signaling.
Wang HJ, et al. J Biomed Sci 2013 Feb 23;20:11.
- 10. Characterization, pharmacokinetics, tissue distribution and antitumor activity of honokiol submicron lipid emulsions in tumor-burdened mice.
Zheng J, et al. Pharmazie 2013 Jan;68(1):41-6.