- API
Any substance that is represented for use in a drug and that, when used in the manufacturing, processing, or packaging ...
- Active Ingredient
Any component that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, ...
- CAS No.
Unique number assigned to a specific chemical (identified by its chemical name) by the American Chemical Society and ...
Matrine
Catalog No. | PI0088 |
---|---|
CAS No. | 519-02-8 |
Molecular Formula | C15H24N2O |
Molecular Weight | 258.43 |
Purity | 98% HPLC |
Package | 25 kg/drum |
Botanical Source | Sophoraflavescens Ait. |
Appearance | White powder |
Storage | Stored in cool and dry places, protected from direct sunlight and heat. |
Shelf Life | 2 years |
Note: This matrine can also be used as reference standards. You can find it under the category of Reference Substance at Herbalext.com. |
Safety Tips of Matrine
Handling of matrine should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.
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Related Applications
Antineoplastic
Each year, more and more people are getting cancer, especially lung and liver cancer. However, there are not enough good anti-cancer drugs. Fortunately, many herbal extracts have good antineoplastic activity. A plant-based diet can help shield you from cancer because plants are rich in anti-inflammatory and antioxidant substances that help us withstand exposure to ultraviolet radiation, air pollution and other noxious substances.
Related Researches
- 1. Matrine, a novel autophagy inhibitor, blocks trafficking and the proteolytic activation of lysosomal proteases.
Wang Z, et al. Carcinogenesis 2013 Jan;34(1):128-38.
- 2. Human ether-a-go-go-related gene channel blockers and its structural analysis for drug design.
Narayana Moorthy NS, et al. Curr Drug Targets 2013 Jan 1;14(1):102-13.
- 3. Arsenic trioxide-induced hERG K(+) channel deficiency can be rescued by matrine and oxymatrine through up-regulating transcription factor Sp1 expression.
Zhang Y, et al. Biochem Pharmacol 2013 Jan 1;85(1):59-68.
- 4. Protective effects of matrine against progression of high-fructose diet-induced steatohepatitis by enhancing antioxidant and anti-inflammatory defences involving Nrf2 translocation.
Zhang HF, et al. Food Chem Toxicol 2013 May;55:70-7.
- 5. F508del-CFTR Rescue: A Matter of Cell Stress Response.
Nieddu E, et al. Curr Pharm Des 2013;19(19):3476-96.
- 6. Combining Oxymatrine or Matrine with Lamivudine Increased Its Antireplication Effect against the Hepatitis B Virus In Vitro.
Ma ZJ, et al. Evid Based Complement Alternat Med 2013;2013:186573.
- 7. Protective role of autophagy in matrine?induced gastric cancer cell death.
Li Y, et al. Int J Oncol 2013 Apr;42(4):1417-26.
- 8. Molecular mechanism of indirubin-3'-monoxime and Matrine in the reversal of paclitaxel resistance in NCI-H520/TAX25 cell line.
Luo SX, et al. Chin Med J (Engl) 2013 Mar;126(5):925-9.
- 9. Effects of matrine on oval cell?mediated liver regeneration and expression of RBP?Jκ and HES1.
Yang ZY, et al. Mol Med Rep 2013 May;7(5):1533-8.
- 10. Matrine suppresses expression of adhesion molecules and chemokines as a mechanism underlying its therapeutic effect in CNS autoimmunity.
Kan QC, et al. Immunol Res 2013 May;56(1):189-96.