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- API
Any substance that is represented for use in a drug and that, when used in the manufacturing, processing, or packaging ...
- Active Ingredient
Any component that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, ...
- CAS No.
Unique number assigned to a specific chemical (identified by its chemical name) by the American Chemical Society and ...
Sinomenine
Catalog No. | PI0125 |
---|---|
CAS No. | 115-53-7 |
Molecular Formula | C19H23NO4 |
Molecular Weight | 329.39 |
Purity | 98% HPLC |
Package | 25 kg/drum |
Appearance | Powder |
Shelf Life | 2 years |
Note: This sinomenine can also be used as reference standards. You can find it under the category of Reference Substance at Herbalext.com. |
Safety Tips of Sinomenine
Handling of sinomenine should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.
Related Applications
Liver Protection
The liver is the primary organ responsible for expelling and breaking down toxins entering the body. In particular, it produces bile, a detoxifying agent metabolically indispensable in breaking down fats from food. Many chemicals from nature could protect liver to help the process of detoxication.
Related Researches
- 1. Sinomenine hydrochloride enhancement of the inhibitory effects of anti-transferrin receptor antibody-dependent on the COX-2 pathway in human hepatoma cells.
Hong Y, et al. Cancer Immunol Immunother 2013 Mar;62(3):447-54.
- 2. Effect of sinomenine on vascular smooth muscle cell dedifferentiation and neointima formation after vascular injury in mice.
Zhu L, et al. Mol Cell Biochem 2013 Jan;373(1-2):53-62.
- 3. Sinomenine hydrochloride inhibits human hepatocellular carcinoma cell growth in vitro and in vivo: involvement of cell cycle arrest and apoptosis induction.
Lu XL, et al. Int J Oncol 2013 Jan;42(1):229-38.
- 4. Analysis of active alkaloids in the Menispermaceae family by nonaqueous capillary electrophoresis-ion trap mass spectrometry.
Chen Q, et al. J Sep Sci 2013 Jan;36(2):341-9.
- 5. Microfluidics assisted synthesis and bioevaluation of sinomenine derivatives as antiinflammatory agents.
Jin J, et al. Eur J Med Chem 2013 Apr;62:280-8.
- 6. Sinomenine inhibits the expression of PD?L1 in the peripheral blood mononuclear cells of mesangial proliferative nephritis patients.
Cheng Y, et al. Mol Med Rep 2013 Apr;7(4):1223-8.
- 7. Determination of alkaloids in Sinomenium acutum by field-amplified sample stacking in capillary electrophoresis with chemiluminescene detection.
Shi G, et al. Luminescence 2013 Feb 7.
- 8. Pharmacological characteristics of Kampo medicine as a mixture of constituents and ingredients.
Satoh H. J Integr Med 2013 Jan;11(1):11-6.
- 9. Sinomenine Protects against Lipopolysaccharide-Induced Acute Lung Injury in Mice via Adenosine A2A Receptor Signaling.
Li J, et al. PLoS One 2013;8(3):e59257.
- 10. Sinomenine Decreases MyD88 Expression and Improves Inflammation-Induced Joint Damage Progression and Symptoms in Rat Adjuvant-Induced Arthritis.
Mu H, et al. Inflammation 2013 Apr 21.